The calculation of risks for preeclampsia is based on maternal factors alone and in combination with any of the biomarkers. Biophysical and biochemical marker values should be obtained within the same gestational age block (11+0 to 14+1, 19+0 to 24+6, 30+0 to 34+6, 35+0 to 37+6 weeks).
- Useful markers at 11+0 to 14+1 weeks: MAP, UTPI and PLGF (or PAPP-A when PLGF is not available).
- Useful markers at 19+0 to 24+6, 30+0 to 34+6 and 35+0 to 37+6 weeks: MAP, UTPI, PLGF and sFLT-1.
The values for PAPP-A, PLGF and sFLT-1 depend on maternal characteristics and reagents used for analysis and they therefore need to be converted into MoMs. In the application above you can either use the MoM values reported by the laboratory or enter the raw data and the MoM values will be calculated.
To ensure that the service you provide is of high quality it is important that you audit the distribution of your mean arterial pressure and uterine artery PI measurements and MoM values of PAPP-A, PLGF and sFLT-1 at regular intervals.
- To audit the distribution of mean arterial pressure measurements please click here.
- To audit the distribution of uterine artery PI measurements please click here.
- To audit the distribution of MoM values of PAPP-A please click here.
- To audit the distribution of MoM values of PLGF please click here.
- To audit the distribution of MoM values of sFLT-1 please click here.
For more information on the background of this application please click here.
This software is based on research carried out by The Fetal Medicine Foundation. Neither the FMF nor any other party involved in the development of this software shall be held liable for results produced using data from unconfirmed sources. Clinical risk assessment requires that the ultrasound and biochemical measurements are taken and analyzed by accredited practitioners and laboratories.