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First trimester urine free beta hCG, beta core, and total oestriol in pregnancies affected by Down's syndrome: implications for first-trimester screening with nuchal translucency and serum free beta hCG.
Spencer K, Noble P, Snijders RJ, Nicolaides KH.
Prenat Diagn 1997;17:525-38. -
The maternal insulin-like growth factor (IGF) and IGF binding protein response to trisomic pregnancy during the first trimester: a possible diagnostic tool for trisomy 18 pregnancies.
Miell JP, Langford KS, Jones JS, Noble P, Westwood m, White A, Nicolaides KH.
J Clin Endocrinol Metab 1997;82:287-92.